Case Reports
A case of hypotension and heart rate changes on rechallenge with a low dose of clozapine with no apparent secondary cause
Authors:
M. L. Harshini ,
Colombo North Teaching Hospital, LK
About M. L.
University Psychiatry Unit
A. I. W. Fernando,
Colombo North Teaching Hospital, LK
About A. I. W.
University Psychiatry Unit
H. M. T. S. Abayawickrama,
Colombo North Teaching Hospital, LK
About H. M. T. S.
University Psychiatry Unit
M. I. N. Ikram,
Colombo North Teaching Hospital, LK
About M. I. N.
University Psychiatry Unit
S. Rajapakse,
Colombo North Teaching Hospital, LK
About S.
Cardiology Unit
A. Hapangama
University of Kelaniya, LK
About A.
Department of Psychiatry, Faculty of Medicine
Abstract
Clozapine is known to cause innocuous as well as severe and or fatal cardiovascular side effects. These side effects are commonly reported at the initiation of clozapine therapy. We report a patient who was stable on clozapine for several years but in whom we had to withhold clozapine for medical reasons and subsequently developed significant hypotension and heart rate changes when rechallenged with a small dose of clozapine.
How to Cite:
Harshini, M.L., Fernando, A.I.W., Abayawickrama, H.M.T.S., Ikram, M.I.N., Rajapakse, S. and Hapangama, A., 2022. A case of hypotension and heart rate changes on rechallenge with a low dose of clozapine with no apparent secondary cause. Sri Lanka Journal of Psychiatry, 13(2), pp.52–54. DOI: http://doi.org/10.4038/sljpsyc.v13i2.8350
Published on
31 Dec 2022.
Peer Reviewed
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