Brief Reports
Clozapine induced severe weight loss in resistant schizophrenia managed with risperidone add-on therapy
Authors:
M. Chandradasa ,
University of Kelaniya, Ragama, LK
About M.
Department of Psychiatry, Faculty of Medicine
Colombo North Teaching Hospital, Ragama
C. S. Kuruppuarachchi,
General Sir John Kotelawala Defence University, Colombo, LK
L. C. Rathnayake,
National Institute of Mental Health, Angoda, LK
K. A. L. A. Kuruppuarachchi
University of Kelaniya, Ragama, LK
About K. A. L. A.
Department of Psychiatry, Faculty of Medicine
Colombo North Teaching Hospital, Ragama
Abstract
Clozapine is prescribed for resistant schizophrenia. It is usually associated with weight gain. There have been only a few reports of weight loss associated with clozapine treatment and we report two patients from Sri Lanka. The first patient lost 27% of bodyweight on clozapine while the second lost 17%. Both were clinically stable on clozapine, with marked reduction of psychotic symptoms. Adding risperidone helped to regain the lost weight in the described patients.
How to Cite:
Chandradasa, M., Kuruppuarachchi, C.S., Rathnayake, L.C. and Kuruppuarachchi, K.A.L.A., 2020. Clozapine induced severe weight loss in resistant schizophrenia managed with risperidone add-on therapy. Sri Lanka Journal of Psychiatry, 11(2), pp.38–39. DOI: http://doi.org/10.4038/sljpsyc.v11i2.8259
Published on
02 Dec 2020.
Peer Reviewed
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